tert-Butyl 3-(cyanomethylene)azetidine-1-carboxylate
tert-Butyl 3-(cyanomethylene)azetidine-1-carboxylate
CAS: 1153949-11-1
Molecular Formula: C10H14N2O2
tert-Butyl 3-(cyanomethylene)azetidine-1-carboxylate - Names and Identifiers
tert-Butyl 3-(cyanomethylene)azetidine-1-carboxylate - Physico-chemical Properties
| Molecular Formula | C10H14N2O2 |
| Molar Mass | 194.23 |
| Density | 1.215 |
| Boling Point | 309.7±35.0 °C(Predicted) |
| Appearance | powder to crystal |
| Color | White to Orange to Green |
| pKa | -1.88±0.20(Predicted) |
| Storage Condition | under inert gas (nitrogen or Argon) at 2-8°C |
tert-Butyl 3-(cyanomethylene)azetidine-1-carboxylate - Risk and Safety
| UN IDs | UN 3439 6.1/PG III |
| Hazard Class | 6.1 |
| Packing Group | III |
tert-Butyl 3-(cyanomethylene)azetidine-1-carboxylate - Introduction
3-(Cyanomethylene) azetidine-l-carboxylic acid tert-butyl ester (abbreviation CN,CAS number: 87674-68-8) is an organic compound. The following is a detailed description of its nature, use, formulation and safety information:
Nature:
-Appearance: colorless to slightly yellow liquid
-Molecular formula: C9H15NO2
-Molecular weight: 169.22g/mol
-Melting point:-20°C
-Boiling Point: 145-147°C
-Density: 0.998g/cm3
-refractive index: 1.459-1.461
Use:
CN is often used as an intermediate in fine organic synthesis and has high reactivity. It can be used to synthesize a variety of organic compounds, such as pharmaceutical intermediates, dyes and pesticides.
Method:
A commonly used method for preparing CN is obtained by reacting hydrogen cyanide and 2-methoxycyclobutanyl bromide, and then esterifying with a substrate. Specific steps are as follows:
1. 2-methoxycyclobutane bromide (C9H17BrO) was reacted with sodium cyanide (NaCN) to obtain 2-methoxycyclobutane cyanide (C9H16NOCN).
2. Cyanide 2-methoxycyclobutane was reacted with tert-butanol (C4H10O) to obtain CN.
Safety Information:
CN is a flammable liquid, so avoid fire during storage and operation. Contact with skin can cause irritation, should wear appropriate protective equipment. Avoid inhaling vapors and operate in a well-ventilated area. If inhaled or exposed, call your doctor immediately and provide the relevant chemical information.
Nature:
-Appearance: colorless to slightly yellow liquid
-Molecular formula: C9H15NO2
-Molecular weight: 169.22g/mol
-Melting point:-20°C
-Boiling Point: 145-147°C
-Density: 0.998g/cm3
-refractive index: 1.459-1.461
Use:
CN is often used as an intermediate in fine organic synthesis and has high reactivity. It can be used to synthesize a variety of organic compounds, such as pharmaceutical intermediates, dyes and pesticides.
Method:
A commonly used method for preparing CN is obtained by reacting hydrogen cyanide and 2-methoxycyclobutanyl bromide, and then esterifying with a substrate. Specific steps are as follows:
1. 2-methoxycyclobutane bromide (C9H17BrO) was reacted with sodium cyanide (NaCN) to obtain 2-methoxycyclobutane cyanide (C9H16NOCN).
2. Cyanide 2-methoxycyclobutane was reacted with tert-butanol (C4H10O) to obtain CN.
Safety Information:
CN is a flammable liquid, so avoid fire during storage and operation. Contact with skin can cause irritation, should wear appropriate protective equipment. Avoid inhaling vapors and operate in a well-ventilated area. If inhaled or exposed, call your doctor immediately and provide the relevant chemical information.
Last Update：2024-04-09 02:00:41
Supplier List
Spot supply
Product Name: Baricitinib Impurity 10 Visit Supplier Webpage Request for quotationCAS: 1153949-11-1
Tel: 0714-3999186
Email: 2853786052@qq.com
Mobile: 86+15671228036
QQ: 2853786052
Wechat: 15671228036
Product Name: 1-Boc-3-(cyanomethylene)azetidine Visit Supplier Webpage Request for quotation
CAS: 1153949-11-1
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
CAS: 1153949-11-1
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
Spot supply
Product Name: 1-Boc-3-(cyanomethylene)azetidine Request for quotationCAS: 1153949-11-1
Tel: 17806220283
Email: info@samelabs.com
Mobile: +86178-0622-0283
QQ: 9291866
Wechat: +86178-0622-0283
WhatsApp: +86178-0622-0283
Linkedin: samelabs
Product Name: 1-Boc-3-(cyanomethylene)azetidine Request for quotation
CAS: 1153949-11-1
Tel: 01060279497
Email: sales02@cooperate-pharm.com
Mobile: 15646567669
QQ: 3257161785
Send QQ message
CAS: 1153949-11-1
Tel: 01060279497
Email: sales02@cooperate-pharm.com
Mobile: 15646567669
QQ: 3257161785
Spot supply
Product Name: Baricitinib Impurity 10 Visit Supplier Webpage Request for quotationCAS: 1153949-11-1
Tel: 0714-3999186
Email: 2853786052@qq.com
Mobile: 86+15671228036
QQ: 2853786052
Wechat: 15671228036
Product Name: 1-Boc-3-(cyanomethylene)azetidine Visit Supplier Webpage Request for quotation
CAS: 1153949-11-1
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
CAS: 1153949-11-1
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
Spot supply
Product Name: 1-Boc-3-(cyanomethylene)azetidine Request for quotationCAS: 1153949-11-1
Tel: 17806220283
Email: info@samelabs.com
Mobile: +86178-0622-0283
QQ: 9291866
Wechat: +86178-0622-0283
WhatsApp: +86178-0622-0283
Linkedin: samelabs
Product Name: 1-Boc-3-(cyanomethylene)azetidine Request for quotation
CAS: 1153949-11-1
Tel: 01060279497
Email: sales02@cooperate-pharm.com
Mobile: 15646567669
QQ: 3257161785Send QQ message
CAS: 1153949-11-1
Tel: 01060279497
Email: sales02@cooperate-pharm.com
Mobile: 15646567669
QQ: 3257161785
View History